There is considerable overlap between the diagnosis of pancreatic cancer and the staging of the cancer. The results of various diagnostic tests will indicate how far the cancer has progressed and determine the stage. Subsequent decicions about treatment will be based upon the stage assigned.
Although different stages carry different prognoses, it is important to remember that the Median isn't the Message (an excellent article regarding prognoses and statistics by Stephen Jay Gould).
The charts below are part of a very common system used by doctors to stage pancreatic tumors. These particular charts are for pancreatic carcinoma. The staging system varies slightly for tumors of the bile duct or ampulla of Vater.
The stage of a pancreatic cancer is determined by 3 factors: T, N, and M. A value is assigned for each of these factors based on the diagnostic test results. Click on these links to see the how each factor is ranked or scaled.
T= location and size of the tumor
N= evidence of metastases in lymph nodes close to the cancer
M= evidence of distant metastases
| Stage Grouping for Primary Tumors of the Exocrine Pancreas | |||
|---|---|---|---|
| Stage | Tumor | Regional Lymph Nodes | Distant Metastases |
| Stage 0 | Tis | N0 | M0 |
| Stage IA | T1 | N0 | M0 |
| Stage IB | T2 | N0 | M0 |
| Stage IIA | T3 | N0 | M0 |
| Stage IIB | T1 T2 T3 |
N1 N1 N1 |
M0 M0 M0 |
| Stage III | T4 | any N | M0 |
| Stage IV | any T | any N | M1 |
| Definition of Tumor (T) | |
| TX | Primary tumor cannot be assessed |
| T0 | No evidence of primary tumor |
| Tis | In situ carcinoma |
| T1 | Tumor limited to the pancreas, 2 cm or less in greatest dimension |
| T2 | Tumor limited to the pancreas, more than 2 cm in greatest dimension |
| T3 | Tumor extends directly into any of the following: duodenum, bile duct, peripancreatic tissues |
| T4 | Tumor extends directly into any of the following: stomach, spleen, colon, adjacent large vessels |
| Definition of Regional Lymph Nodes (N) | |
| NX | Regional lymph nodes cannot be assessed |
| N0 | No regional lymph node metastasis |
| N1 | Regional lymph node metastasis pN1a= metastasis in a single regional lymph node pN1b= metastasis in multiple regional lymph nodes |