|*DISCLAIMER: This page is an unmoderated forum, and the opinions expressed herein do not necessarily reflect the viewpoint of The Johns Hopkins Medical Institutions. Patients are advised to consult their personal physicians before making any medical decisions. |
I also just recently had the genetic testing done through my hospital and of the 82 genes tested, only 1 was a variant, the RECQL4, and, for this gene, the relationship is 'of uncertain/unknown significance'. (I have no idea what those letters and number stand for, but google indicates in role in the body.)
As part of the genetic process, I also put together a genealogical chart of all my 12 siblings, my parents, aunts, uncles and cousins on both sides, my grandparents and the siblings of my grandmother who died of kidney cancer in 1955.
My grandmother is the only one who ever died of cancer; the number of other cases of cancer has been small and the impact on the long term health of the individual has been negligible.
So, what is the bottom line? Pancreatic cancer can have pre-disposing conditions, but mostly the occurrence is (as of today), random.
My genetics staff gave me a wonderful pie chart that shows this, and, if it is possible to attach things to these posting, I will be glad to do so. Basically, it says that heredity influences account for 5-10%, familial 10-20%, and sporadic, 70-80%. We should not take these as hard and fast numbers, but they show the relative magnitude. And, hopefully, future studies can pin down factors more precisely and lead to earlier diagnoses, when the cancer is most amenable to treatment.
My best to all,
PS - nobody in my circle has put any blame on me for my cancer. I feel great
sadness that anyone has done this to others.
Reply to this message | Return to Main Message List