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Pancreas Cancer

Major sequencing paper was posted 08/14/2017 01:39 pm by Dr. Hruban
E-mail Address: rhruban@jhmi.edu

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The Cancer Genome Atlas (TCGA) research network (the US government's effort to sequence the DNA in all of the major types of cancer), just published their results from a complete genetic analysis of 150 pancreatic cancers! In the August 14th issue of the journal CancerCell (http://www.cell.com/cancer-cell/fulltext/S1535-6108(17)30299-4), the TCGA authors describe a detailed integrated (DNA, RNA and protein) analysis of the 150 pancreatic cancers. The major genes driving pancreatic cancer are described, and the authors identified two main subtypes of pancreatic cancer (basal-like/squamous and classical/progenitor). While this study does not have direct patient impact yet, it does represent a major milestone in our understanding of this disease.
Special congratulations to the many scientists from Johns Hopkins who contributed to this study!
Dr. Hruban

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*DISCLAIMER: This page is an unmoderated forum, and the opinions expressed herein do not necessarily reflect the viewpoint of The Johns Hopkins Medical Institutions. Patients are advised to consult their personal physicians before making any medical decisions.
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