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Pancreas Cancer

Metformin and Folfirinox was posted 01/29/2013 11:49 am by JeffB
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Indeed, Metformin may be the reason my wife is alive and NED today after being diagnosed with inoperable adenocarcinoma pancreatic cancer with liver mets in July 2011. Metformin is now proven to eradicate the pancreatic cancerous stem cells not targeted by chemotherapy and also kills cancerous tumors preventing them from recurring. Here is a brief description of my wife's journey:

She was diagnosed in 2006 with Type II Diabetes at which time she began taking Metformin 850mg 2x daily. Even after diet and exercise and losing 40 pounds and becoming physically fit, she still needed the Metformin to stabalize her sugars. She was diagnosed 5 years later in July 2011 with pancreatic cancer and began Folfirinox chemotherapy along with her daily dosages of Metformin from August 2011 through June 2012 tolerating 10 months/19.5 sessions of treatment without a break, never a change in her white blood cell counts. The 5cm tumor found on the body of her pancreas reduced in size to 4mm after the first 6 months of treatments and the 2 spots measuring approximately 1cm each disappeared.

After an additional 4 months of treatments a June 2012 CTscan revealed the 4mm tumor became scar tissue measuring less than 2mm with no metabolic activity and the liver remained clear. There was no evidence of new or progressive metastatic disease and no tumor recurrence.

Chemotherapy stopped in June 2012 and since then has only been on Metformin 850mg 3x daily. CTscans in September 2012 and December 2012 both No Evidence of Disease. She is returning from a 5 week vacation over-seas tomorrow and will have her monthly blood work drawn and another quarterly CTscan is scheduled for late February or early March.

She an anomaly of some sort having completed a 10k marathon last December and runs/jogs 6 miles daily. Now 19 months since diagnosis and NED for the last 7 months, people assume she had the whipple surgery, SHE DID NOT! In fact Folfirinox and Metformin did all the work with God's infinite Mercy and Grace.

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*DISCLAIMER: This page is an unmoderated forum, and the opinions expressed herein do not necessarily reflect the viewpoint of The Johns Hopkins Medical Institutions. Patients are advised to consult their personal physicians before making any medical decisions.
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