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If you are taking drugs to help keep your red blood counts up (Epogen, Aranesp), you will use up the iron because it is used to make more red blood cells. Also I guess your body would using it constantly if you are on a chemo that makes your red blood cells drop, and your body is trying to make more.
I am not sure of the most concerning values and when they decide to treat. We even asked my mom's oncologist about it this week because her values are low (iron 14), but all he said was 'take iron pills, as much as you can tolerate'. She was already taking iron pills. We didn't talk about IV iron.
But I read on the instructions with the Aranesp shot that you should have
iron stores (ferritin) ideally greater then 100.
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