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Pancreas Cancer

cpi-613: a new clinical trial was posted 07/29/2009 02:21 pm by elliott
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My father, stage 4B, passed away last month at the age of 76 after fighting PC for over two years. Much of the two years gained was due to GTX. You can do a search on my name to see my father's story. Near the very end, he tried a drug for which there is a new clinical trial. It's called CPI-613. It's a phase I/II, with sites in Beverly Hills, Vancouver BC, and the Bronx (the latter site focused more exclusively on PC). We heard about it by accident, through a relative whose business acquaintance is also a business associate of the drug's company. By the time my father started receiving the drug, he didn't have enough time to get in multiple cycles, to do dose escalation, etc., because soon after starting he had complications (a stroke) from a blood clot due to the cancer. He got through one month, missing the middle two of the six doses. On the positive side, his late-stage pain mysteriously and miraculously disappeared after the second dose to the point of not needing any more hydromorphone or other pain killers until close to death, but the docs honestly were not sure whether that was from the drug or the stroke.

A search on this board shows that this drug has never been mentioned here. If you do a google search on cpi-613, you'll find all the info. Aside from trying to do my part for society against PC after going through it with my father, I'm certainly interested in knowing if this drug would've worked had he had more time. My own feeling is that if you're going to try an experiemntal drug, do it earlier, and instead of, not after, second-line chemo or Cyberknife, things that don't really offer much hope or time for those in stage 4 and which take up valuable time that could've been used on something potentially longer-lasting. And a trial like this seems to offer more hope than just adding another ingredient into an otherwise known chemo cocktail. Good luck.

elliott

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